-
Continue reading →: A primer on the impact of gene therapies and CASGEVY on CRISPR AG and the industryCASGEVY approval CASGEVY is a groundbreaking gene therapy, owned by CRISPR AG (CRSP) and Vertex (VRTX) specifically designed for the treatment of sickle cell disease (SCD) in individuals aged 12 and older who experience frequent vaso-occlusive crises (VOCs). Developed through a collaboration between Vertex Pharmaceuticals and CRISPR Therapeutics, CASGEVY stands…
-
Continue reading →: China’s Economic Crossroads: Navigating the Delicate BalanceGiven China’s significant role as a key player in the global economy, I maintain a vigilant and analytical approach to Professor Michael Pettis’ insights on its economic strategies. Pettis has long maintained that China’s reliance on supply-side stimulus is a misstep. This is pivotal as China, being the world’s second-largest…
-
Continue reading →: Loose thoughts in a time of uncertaintyAs we navigate the currents of today’s financial markets, we’re witnessing a striking contrast between the resilience of equities and the cautious stance of the bond market. Equity markets, it seems, are choosing to overlook looming challenges, clinging to a narrative of a ‘soft landing’ for the economy. On the…
-
Continue reading →: Dissecting the Causes of Inflation
The macro landscape is painting a fascinating picture of the inflationary environment, especially when we dive deep into the underlying narratives. The NBER folks help us get a more precise picture of what caused inflation. They concluded the following: 1. First, let’s not underestimate the magnitude of the U.S.’s fiscal…
-
Continue reading →: Quick Takes: Grayscale’s Victory & The Evolution of Cryptocurrency RegulationExecutive Summary: Grayscale Investments’ recent court ruling in favor of launching the first-ever Bitcoin ETF in the U.S. is a watershed moment for the cryptocurrency ecosystem. Beyond the immediate market reaction, this event points towards a maturing regulatory environment and sets a potential precedent for the broader adoption of crypto-focused…
-
Continue reading →: A Macro Perspective on Wealth Transfers: From the French Revolution to BitcoinWealth transfers have, throughout history, acted as a cornerstone of societal evolution. These transfers are not mere shifts of assets from one hand to another; they represent changes in power dynamics, socio-economic structures, and often herald a new epoch in human civilization. The French Revolution: A Primer on Wealth Transfer…
-
Continue reading →: Gene Therapy Breakthroughs on the HorizonIn our constant endeavor to find companies ready to launch products and services in the gene therapy space, we come across Vertex Pharmaceuticals and CRISPR Therapeutics, who alongside bluebird bio, are penning a new chapter in the story of gene therapy for sickle cell disease. Now, to bring this into…
-
Continue reading →: Macro Note: The Deflationary Dragon
The macro narrative is missing a giant piece of the puzzle. Dive deep into the data, and an understated deflationary shock from China becomes evident. Surprisingly, in the face of a 6% depreciation of the yuan against the USD over the past 12 months – an event that, by all…
-
Continue reading →: Rethinking China: From Bullish Optimism to Cautious RealismOver the past decade, I’ve been notably bullish on China, driven by their remarkable growth trajectory since the 1970s and the potential for their equities to dominate globally. However, post-2020, certain events have prompted a reevaluation of this stance. The emergence of the pandemic in 2020, coupled with the unchallenged…
-
Continue reading →: FedNow, Stablecoins, and the New Frontier Eurodollar MarketIn a recent radio interview on the U.S. banking crisis, I talked about the urgent need for banking business models to adapt to the lightning-fast pace of real-time settlements. Why? Because in this age of social media and digital banking, when bank runs happen, they happen at a pace that’s…
Hi Fren,
Pepe Maltese
I used to trade inside the machine. Now I just raid it.
I publish two high-conviction setups daily — one momentum, one turnaround — filtered through tape structure, volume shifts, and misaligned narratives.
Some of these turn into full trades. A few evolve into deeper stories. The rest get cut.
This isn’t education. This is intelligence.
I don’t run ads. I don’t sell dreams. I track price, watch structure, and call bullshit when the story breaks.
Follow the setups. Fade the noise. Stick it to the man.
Let’s connect
Join!
Stay updated with our latest ideas by joining our newsletter.
Investment Gems 